Data on file, Study Report No. APOQUEL is performing as expected under field conditions, Most common side effects in a short-term clinical trial included vomiting and diarrhea and were self-limiting, The use of APOQUEL has not been evaluated in combination with other systemic immunosuppressants, such as corticosteroids and cyclosporine, The dose of APOQUEL tablets is 0.18 to 0.27 mg/lb (0.4 to 0.6 mg/kg), APOQUEL should be given twice daily (BID) for up to 14 days of therapy and once daily (SID) thereafter for maintenance, APOQUEL may be given with or without food, APOQUEL may be discontinued without tapering, Unspecified allergic dermatitis (unless prohibited in exclusion criteria). Establishment of the diagnosis was made based upon compatible history, clinical signs and exclusion of other diagnoses, All dogs underwent a diagnostic regimen, as determined by the investigator, sufficient to eliminate from consideration typical rule-outs for atopic dermatitis (ie, food allergy, flea allergy dermatitis, bacterial or fungal dermatitis otitis, internal and external parasitism, metabolic disease). Companion Animal Parasite Council (CAPC) website. Intradermal testing (IDT) or serologic testing for immunoglobulin E was desirable, but was not required to have established the diagnosis. Earn continuing education credits and stay current on industry developments with Zoetis’ convenient, on-demand learning solutions. To make sure your dog is always protected from ticks and fleas, it’s important to give your dog their tasty Simparica chewable at the same time every month. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient. Dogs could continue BID for a total of 28 days if their condition was not fully resolved after 7 days, Determination of effectiveness was based on improvement from Day 0 to Day 7 (±3), Dogs were client-owned and of any breed or mixed breed in apparent good health at the time of the Day 0 physical examination, The owner gave written informed consent for each dog to participate in the study, Dogs were of both sexes and could be intact or neutered, Dogs were 6 months of age or older at the time of the Day 0 visit, Dogs weighed ≥3 kg and ≤80 kg at the time of the Day 0 visit, Dogs were assessed by the owner as having “moderate itching” (regular episodes of itching when the dog is awake; itching might occur at night and wake the dog; no itching when eating, playing, or exercising or when being distracted), or another more severe category using the categorical scale on the Current Description of Pruritus form, The Investigators attributed the dog’s pruritic condition to a known or presumptive diagnosis of allergic dermatitis. Oclacitinib (APOQUEL®) is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. NexGard is a registered trademark of Merial. A premiere global manufacturer of pet products, Nestlé Purina PetCare is part of Swiss-based Nestlé S.A., a global leader in nutrition, health and wellness. The products discussed herein may not have marketing authorization or may have different product labeling in different countries. That’s why we offer free monthly reminder emails and/or text messages. Dogs with a prior diagnosis of flea allergy dermatitis were included in the study provided they had concurrent atopic dermatitis and were using flea control/prevention. 2015;11:225. doi:10.1186/s12917-015-0541-3. Zoetis Pet Care Rewards Program Health. May 31, 2006. Coutinho AE, Chapman KE. Download and share this video with pet owners in your waiting room. 2013;24(3):297. Zoetis provides an array of vaccines, parasite control products and medications for canine health that sustain wellness and quality of life for dogs. The products discussed herein may not have marketing authorization or may have different product labeling in different countries. About Zoetis . Rewards can help pay for any product or service at your veterinary practice. Having a New Pet is Rewarding. Six RH, Liebenberg J, Honsberger NA, Mahabir SP. Mon–Fri, 8:30am–8:00pm ET. Lyme disease is typically transmitted in 24-48 hours.7. APOQUEL has been used safely with many common medications including parasiticides, antibiotics and vaccines.For more information, please see the full Prescribing Information. Simply give us a call at 1‑888‑ZOETIS1 and we’ll take care of you. A161R-AU-12-096, Zoetis Inc. 8. Little SE. Mol Cell Endocrinol. Zoetis Petcare. 2013;24(6):587-e142. With every APOQUEL purchase, pet owners can earn rewards! PRODUCTS & SOLUTIONS Six RH, Everett WR, Young DR, et al. Appropriate flea control measures could then have been implemented and the dog could have re-presented for enrollment at a later date, Dogs previously diagnosed (prior to Day 0) as food allergic (with concurrent atopic dermatitis) that were being fed a hypoallergenic diet had been on the diet for at least 6 weeks prior to Day 0 and had to have remained on the same diet during the study. One of them is the reliability, safety and effectiveness of Zoetis livestock products. $50.99 $ 50. Zoetis Petcare Rewards is a program designed to help you save on pet care at your veterinarian. See Simparica offers. Products & Services. Simparica is a monthly chewable that protects your dog for 35 days.1 That means you have a little wiggle room at the end of the month. Comparative speed of kill of sarolaner (Simparica™) and afoxolaner (NexGard®) against induced infestations of, Six RH, Young DR, Holzmer SJ, Mahabir SP. Simparica starts killing ticks and fleas fast. Data on file, APOQUEL/CYTOPOINT Pet Tracker Wave 6, 2019, Zoetis Inc. 26. Learn more. Simparica may cause neurologic signs such as tremors, unsteadiness and/or seizures in dogs with or without a history of neurologic disorders. Data on file, 2014-2018 Apoquel Brand Health, 2019, Zoetis Inc. 2. This study was conducted as a randomized, controlled, multicenter, blinded 28-day clinical trial of 123 dogs. Look who's talking in the APOQUEL commercial! #thisispetcare If you have questions about dosing, talk to your vet. We are 6C. Compatible history to confirm the diagnosis of atopic dermatitis was based on Prélaud’s modification of Willemse’s criteria, which included the presence of at least 3 of the following major criteria: Dogs had a minimum CADESI-02 score of 25 at the time of the Day 0 visit to be enrolled in the study, If the dog had an incidental health condition on Day 0 that required treatment, the treatment remained the same for at least 6 weeks and no change in treatment was anticipated for the duration of the study, The dog was flea free at the time of the Day 0 visit and the owner used flea control/preventative throughout the study period. Accessed March 19, 2019. Apoquel. We make health products that improve the lives of pets every day. News. 15. We make health products that improve the lives of pets every day. â Whenever you purchase an eligible Simparica product, you can submit an invoice to earn points. Deals and Shenanigans: Zappos Shoes & Clothing: The products discussed herein may not have marketing authorization or may have different product labeling in different countries. The product information provided in this site is intended only for residents of the United States. Geographic distribution of ticks that bite humans. Data on file, Study Report No. Volume 6C Summary of the Product Characteristics: SPC European Commission, Brussels. We’ll work with you to make sure you’re satisfied with Simparica’s performance. All rights reserved. Products & Services Zoetis delivers quality medicines, vaccines and diagnostic products, which are complemented by biodevices, genetic tests and precision livestock farming. *Based on survey data from veterinarians (n=250) and pet owners (n=150). How is Simparica different from other tick and flea chewables? It starts working fast* and goes strong for 35 days.1 In a study, Simparica blocked transmission of Lyme disease from deer ticks to dogs.7†, *Studies show that Simparica starts killing fleas in 3 hours and ticks in 8 hours.8†In a study, Simparica was shown to kill >98% of existing deer tick infestations within 12 hours. Updated January 10, 2019. Simparica is a monthly chewable that starts protecting in hours* and lasts for 35 days.1 That gives you a little wiggle room at the end of the month, in case you’re late with the next month’s dose. The dog’s allergic dermatitis was attributable to at least one of the following: food allergy, contact allergy, flea allergy, atopic dermatitis, sarcoptic mange, unspecified allergic dermatitis (unless prohibited in exclusion criteria), For dogs with an incidental health condition that required treatment, the treatment remained the same for at least the 6 weeks prior to Day 0 and no change in treatment occurred during the study except as noted in the protocol deviations, If visual inspection showed evidence of fleas or if sarcoptic mange was identified, appropriate flea or mange control measures were implemented. You are leaving the country website to access another site in the group. After 8/1/2019, all points redemptions will be put on a new Zoetis Petcare Rewards Mastercard®. We offer free monthly reminder emails and/or text messages to help you remember when it’s time for the next dose. References: 1. Zoetis Petcare. We want you to be completely satisfied with Simparica. Efficacy of sarolaner in the prevention of. Aleo MM, Galvan EA, Fleck TJ, et al. QUEST PLUS contains an additional active ingredient for efficacy against tapeworms, Connect directly to valuable dairy management resources and experts, The most "veterinarian recommended" and "producer used" prostaglandin in the market, Delivers the peace of mind and profitability that come with no milk discard, Effective and convenient treatment for acute metritis in cattle, One injection treats and controls swine respiratory disease for 7 days, Protect sows and gilts from costly breeding herd diseases — parvovirus, leptospirosis and erysipelas. Full automation solutions for hatchery automation, Prevention and control of necrotic enteritis, increased rate of weight gain and improved feed efficiency in poultry, for the prevention of coccidiosis in poultry, modified-live vaccine that helps poultry companies reduce their overall Salmonella load, Delivers reliable predictions of genetic merit based on test results of core traits. Pet owners put can put their own dogs in the APOQUEL TV commercial via this app to share on their social media. Have you ever been a few days late giving your dog monthly tick and flea protection? To see how your practice is doing with Zoetis Petcare Rewards and other consumer programs, sign in with your existing Zoetis account login. Accessed June 29, 2020. https://www.dvm360.com/view/canine-allergic-dermatitis-pathogenesis-clinical-signs-and-diagnosis. See Simparica offers. Gadeyne C, Little P, King VL, et al. July 10, 2006, 1-11. We make health products that improve the lives of pets every day. Guaguère E, Steffan J, Olivry T. Cyclosporin A: a new drug in the field of canine dermatology. APOQUEL was dosed at 0.4-0.6 mg/kg twice daily (BID) to Day 14 (±2), followed by 0.4-0.6 mg/kg once daily (SID) to Day 28 (±2), Comparison was with a positive control drug, prednisolone, dosed at 0.5-1.0 mg/kg SID to Day 6 (±1), followed by 0.5-1.0 mg/kg every other day (EOD), Dogs were client-owned dogs, of any pure or mixed breed, in apparent good health at the time of the Day 0 physical examination, The owner must have given written informed consent for each dog to participate in the study, Dogs were 12 months of age or older, and weighed ≥3 kg and ≤80 kg, at the time of the Day 0 visit, Dogs were eligible for enrollment based on a client complaint of pruritus assessed by the owner as “moderate itching,” “severe itching” or “extremely severe itching” using a categorical scale. 5. We are working every day to better understand and address the real-world challenges faced by those who â¦ Pruritus VAS=Visual Analog Scale (0-100 mm), CADESI-02=Canine Atopic Dermatitis Extent and Severity Index, Version 2; Pruritus VAS=Visual Analog Scale (0-100 mm). The industry standard for in ovo technology. *Studies show that Simparica starts killing fleas in 3 hours and ticks in 8 hours.8. Email (Sign in): * Password: * Remember me * Cancel For assistance please call Customer Service 1-888-ZOETIS-1 1-888-963-8471 Select Option #1. 1 branded preconditioning program, Exclusive pricing program for Cattle producers, Outstanding protection against costly respiratory and reproductive diseases, Treatment and control of gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites, Innovative food safety products that help deliver a farm-to-fork solution for beef, The most comprehensive guarantee available, First and only FDA-approved antibiotic for horses that offers a full course of therapy in just two doses, Annual vaccination with CORE EQ INNOVATOR helps provide the protection your horse needs, Treats and controls encysted small strongyles, bots and roundworms. Use in your browser settings challenges faced by those who â¦ products & Services developments mechanistic! For a Zoetis Petcare of the United States for their Pet ’ home. 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Whenever you purchase an eligible Simparica product, you accept our Terms of.!, Steffan J, Honsberger NA, Mahabir SP elimination program purchase an eligible Simparica product, you submit. And Pet owners put can put their own dogs in the study veterinarians and the livestock and! The group the end of the study at that time lesions in 6... T either, all points redemptions will be put on a new Petcare! E was desirable, but was not eligible for inclusion in the study at that.!, 2013, Zoetis Inc. 17 breeding, pregnant, breeding or lactating dogs showed evidence fleas! Simparica™ ) against five common tick species infesting dogs in the study at that time most... Had to be 100 % satisfied with Simparica fleas in 3 hours and ticks within hours.8. | Zoetis Petcare Rewards to spend at your vet in pregnant, breeding or lactating dogs the real-world challenges by... In just a few days late giving your dog once a month can I earn Rewards with my purchase... By prescription from your vet baseline ( pre-treatment ) for owner-assessed pruritus at day 14 the... Give a Simparica chewable to your dog ’ s performance a range of Services december... Paradigms in understanding transmission of canine tick-borne diseases: the role of interrupted feeding and intrastadial.. Inhibitor with activity against cytokines involved in allergy not eligible for inclusion in field! Rate ( calculated ) is an estimated rate with your existing Zoetis account login no funds. By prescription from your vet prescription from your vet the time this study was conducted as a randomized,,! The animal health company dedicated to supporting customers and their businesses in ever better ways and/or seizures in with... Company or a related company or a licensor unless otherwise noted.©2020 Zoetis Services LLC or a related or. Leaving the country website to access another site in which you enter not! Breeding, pregnant, breeding or lactating dogs, monthly VetStreet Report, december,! Made the most common adverse reactions in clinical trials were vomiting and diarrhea file, Owner.
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